Leptospirosis

Investigations

  • Bacterial culture: Leptospira bacteria remain in the blood of the host for 7-10 days post exposure. After 10 days of initial exposure, the pathogen is visible in the urine as well. Thus, blood and urine samples are used for growing the bacteria in controlled laboratory conditions. 
  • Kidney function and liver function tests help check for the effect of the disease of the functioning of the respective organs.
  • Kidney biopsy (involves examining a sample of nephritic tissue)
  • ELISA (Enzyme-linked Immunosorbent Assay), PCR (polymerase chain reaction) and MAT (microscopic agglutinations test) help detect the presence of specific antibodies. These antibodies are the proteins which are produced by the body’s defense system in response to the infection or foreign bodies.

 

 


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